Preterm birth prevention—Time to PROGRESS beyond progesterone - HHM

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Tuesday, 19 September 2017

Preterm birth prevention—Time to PROGRESS beyond progesterone

Jane E. Norman, Phillip Bennett

There has been huge renewed excitement amongst clinicians and the pharmaceutical industry for the use of progestogens to prevent preterm birth in the 21st century.

A PubMed search shows 792 publications on this topic since 2000. The PROGRESS Study adds to a body of evidence suggesting that the role of progesterone may be more limited than previously thought.

 Preterm birth remains the single biggest cause of neonatal mortality and morbidity worldwide, and effective therapeutic interventions are desperately needed.

It is time to start exploring alternatives, and to progress beyond progesterone for the prevention of preterm birth.